Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | ASPH | Q12797 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31121874 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL28512831 | 0.86 | CLCN2 (0.48) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL19893742 | 0.80 | CLCN2 (0.46) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL29276538 | 0.79 | CLCN2 (0.44) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL20711420 | 0.79 | TAS2R14 (0.48) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL1223395 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1HPGDHSD17B10NOTUM | |
| SCHEMBL28527880 | 0.78 | CFTR (0.39) | NOTUMCTSSCTSKCFTRCES2 | |
| SCHEMBL20702493 | 0.77 | CLCN2 (0.43) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL30307023 | 0.77 | CLCN2 (0.43) | KDM4EALDH1A1HPGDHSD17B10CLCN2 | |
| SCHEMBL21177402 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1HSD17B10TSHRCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740470-B1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA CROP PROTECTION AG (CH) | 2022-05-18 | — | — | EP | disclosed |
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2022-03-15 | — | — | US | disclosed |
| EP-3740470-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | Syngenta Crop Protection AG (CH) | 2020-11-25 | — | — | EP | disclosed |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | SYNGENTA PARTICIPATIONS AG (CH) | 2020-11-05 | — | — | US | disclosed |
| CN-111615508-A | Amidine substituted benzoyl derivatives useful as herbicides | 先正达参股股份有限公司 | 2020-09-01 | — | — | CN | disclosed |
| WO-2019141740-A1 | AMIDINE SUBSTITUTED BENZOYL DERIVATIVES USEFUL AS HERBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11272709-B2 | Amidine substituted benzoyl derivatives useful as herbicides | GLRX3, DDT, BROX | KDM4E 548/4885ALDH1A1 1054/4885HPGD 3033/4885 |
| US-20200345009-A1 | Amidine Substituted Benzoyl Derivatives Useful As Herbicides | GLRX3, DDT, BROX | KDM4E 548/4885ALDH1A1 1054/4885HPGD 3033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.