SCHEMBL2117955

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2116065	0.82	HTT (0.58)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL2116857	0.79	HTT (0.55)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL3619417	0.79	L3MBTL1 (0.50)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL2116548	0.78	HTT (0.54)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL27492622	0.77	HPGD (0.46)	SMN1; SMN2MAPTALDH1A1LMNAHTR1A
	SCHEMBL10371116	0.77	HTT (0.56)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL17544544	0.76	HTT (0.55)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL24975433	0.76	HTT (0.51)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL26971403	0.76	CYP1A2 (0.57)	HTTSMN1; SMN2STAT3MAPTL3MBTL1
	SCHEMBL12775447	0.75	CYP1A2 (0.46)	SMN1; SMN2MAPTL3MBTL1MAPK1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.