Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | STAT3 | P40763 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATP4A | P20648 | 3/20 | 0.42 |
| ▸ | ATP4B | P51164 | 3/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975429 | 0.82 | RXRA (0.45) | L3MBTL1MAPTMAPK1TDP1LMNA | |
| SCHEMBL24975432 | 0.82 | PIN1 (0.40) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL2116065 | 0.80 | HTT (0.58) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL24975462 | 0.78 | SMN1; SMN2 (0.52) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL2116857 | 0.77 | HTT (0.55) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL2117955 | 0.76 | HTT (0.54) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL2116548 | 0.76 | HTT (0.54) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL27438960 | 0.75 | HTT (0.50) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL17904254 | 0.75 | L3MBTL1 (0.47) | HTTSMN1; SMN2STAT3L3MBTL1MAPT | |
| SCHEMBL10371116 | 0.75 | HTT (0.56) | HTTSMN1; SMN2STAT3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005894-A1 | INHIBITOR COMPOUND FOR WNT PATHWAY | 杭州阿诺生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |