Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.40 |
| ▸ | LPL | P06858 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20365272 | 0.90 | ROCK1 (0.54) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL18497263 | 0.87 | ROCK1 (0.44) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL21179831 | 0.85 | PRMT5 (0.41) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL21179837 | 0.84 | AAK1 (0.40) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL21179839 | 0.84 | ROCK1 (0.44) | ROCK1 | |
| SCHEMBL3490524 | 0.83 | PRMT5 (0.57) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL14898149 | 0.80 | ROCK1 (0.51) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL15866726 | 0.79 | ROCK1 (0.48) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL1290116 | 0.79 | ROCK1 (0.54) | ROCK1LIPGLPLCA1CA2 | |
| SCHEMBL20583708 | 0.79 | HPGD (0.54) | ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | ROCK1 2733/4885LIPG 3455/4885LPL 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.