Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA9 | Q16790 | 4/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.37 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20528016 | 0.90 | HIF1A (0.40) | AAK1CA1CA2CA9PRMT5 | |
| SCHEMBL16321506 | 0.88 | TSHR (0.46) | AAK1CA1CA2CA9PRMT5 | |
| SCHEMBL21179836 | 0.87 | HIF1A (0.40) | AAK1CA1CA2CA9PRMT5 | |
| SCHEMBL21179831 | 0.85 | PRMT5 (0.41) | CA1CA2CA9PRMT5WDR77 | |
| SCHEMBL21179838 | 0.84 | ROCK1 (0.46) | CA1CA2CA9PRMT5WDR77 | |
| SCHEMBL21179840 | 0.84 | EPHX2 (0.44) | — | |
| SCHEMBL3413800 | 0.83 | PRMT5 (0.57) | AAK1CA1CA2CA9PRMT5 | |
| SCHEMBL20365272 | 0.82 | ROCK1 (0.54) | CA1CA2CA9PRMT5WDR77 | |
| SCHEMBL22660021 | 0.79 | AAK1 (0.42) | AAK1CA1CA2CA9PRMT5 | |
| SCHEMBL16831556 | 0.79 | LIPG (0.42) | AAK1CA1CA2CA9ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10357036-B2 | Compounds for controlling arthropods | DDT, ACHE, NISCH | AAK1 1189/4885CA1 546/4885CA2 615/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.