SCHEMBL21179846

SCHEMBL21179846

CC(C)(C)C1=CC(=C/N=N/c2ccccc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.40
▸ KMT2A Q03164 5/20 0.38
▸ ATM Q13315 4/20 0.38
▸ NPC1 O15118 2/20 0.38
▸ GPR35 Q9HC97 1/20 0.38
▸ POLB P06746 2/20 0.37
▸ GPR55 Q9Y2T6 1/20 0.37
▸ CYP2D6 P10635 1/20 0.34
▸ ALDH1A1 P00352 5/20 0.33
▸ MAPT P10636 7/20 0.33
▸ HPGD P15428 3/20 0.33
▸ NPSR1 Q6W5P4 2/20 0.33
▸ CES2 O00748 1/20 0.33
▸ PKM P14618 1/20 0.33
▸ CES1 P23141 1/20 0.33
▸ MPI P34949 1/20 0.33
▸ MEN1 O00255 3/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ HSP90AA1 P07900 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13986184 1.00 SMN1; SMN2 (0.40) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL18877802 0.91 SMN1; SMN2 (0.34) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580310 0.88 ATM (0.38) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL14280269 0.86 NPC1 (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13749169 0.86 ATM (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580408 0.85 NPC1 (0.37) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL141575 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13986178 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL15893570 0.85 NPC1 (0.36) SMN1; SMN2KMT2AATMNPC1GPR35
SCHEMBL13580484 0.85 ATM (0.36) SMN1; SMN2KMT2AATMNPC1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3415989-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS KYOCERA DOCUMENT SOLUTIONS INC (JP) 2020-07-22 — — EP disclosed
US-10635009-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-04-28 — — US disclosed
US-10359713-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2019-07-23 — — US disclosed
Send feedback