Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 16/20 | 0.53 |
| ▸ | CCKAR | P32238 | 10/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20098169 | 1.00 | CCKBR (0.53) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL21755181 | 0.88 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL20098042 | 0.88 | CCKBR (0.54) | CCKBRCCKAR | |
| SCHEMBL20866812 | 0.87 | CHRM1 (0.43) | CCKBRCCKARMEN1ALDH1A1KMT2A | |
| SCHEMBL20098149 | 0.86 | CCKBR (0.56) | CCKBRCCKAR | |
| SCHEMBL20098315 | 0.86 | CCKBR (0.50) | CCKBRCCKAR | |
| SCHEMBL20098115 | 0.85 | CCKBR (0.56) | CCKBRCCKAR | |
| SCHEMBL21755227 | 0.85 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL20098127 | 0.85 | CCKBR (0.47) | CCKBRCCKAR | |
| SCHEMBL20098271 | 0.84 | CCKBR (0.54) | CCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358441-B2 | Processes for the preparation of benzodiazepine derivatives | ENANTA PHARMACEUTICALS, INC. (US) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358441-B2 | Processes for the preparation of benzodiazepine derivatives | CYP11B1, CYP11B2, CYP3A5 | CCKBR 528/4885CCKAR 711/4885MEN1 1497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.