Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 5/20 | 0.58 |
| ▸ | AURKA | O14965 | 1/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28143316 | 0.89 | GUSB (0.56) | PDE5AAURKASLC2A1NOX1ALDH1A1 | |
| SCHEMBL28295235 | 0.85 | KDM4E (0.55) | PDE5AALDH1A1GAAPTGESKDM4E | |
| SCHEMBL28142400 | 0.85 | GUSB (0.52) | PDE5AAURKASLC2A1NOX1ALDH1A1 | |
| SCHEMBL21180300 | 0.83 | GAA (0.50) | ALDH1A1GAAPTGESKDM4EMEN1 | |
| SCHEMBL21180297 | 0.79 | PTGES (0.73) | ALDH1A1GAAPTGESKDM4EMEN1 | |
| SCHEMBL21180250 | 0.79 | PTGES (0.49) | ALDH1A1GAAPTGESKDM4EMEN1 | |
| SCHEMBL2062319 | 0.79 | KDM4E (0.73) | PDE5ANOX1ALDH1A1GAAPTGES | |
| SCHEMBL19233099 | 0.79 | PTGES (0.49) | ALDH1A1GAAPTGESKDM4EMEN1 | |
| SCHEMBL29930654 | 0.79 | KDM4E (0.73) | PDE5ANOX1ALDH1A1GAAPTGES | |
| SCHEMBL27196577 | 0.79 | PTGES (0.49) | ALDH1A1GAAPTGESKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240124514-A1 | DEOXYNUCLEOSIDE MODIFIED RUTHENIUM COMPLEX, AND PREPARATION METHOD AND USE THEREOF | Guangzhou Ruby Biotechnology Co., Ltd. (CN) | 2024-04-18 | — | — | US | disclosed |
| US-10358455-B2 | Arene ruthenium complex, preparation method and utilization thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY (CN) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358455-B2 | Arene ruthenium complex, preparation method and utilization thereof | CBR3, CBR1, C1R | PDE5A 4789/4885AURKA 3231/4885SLC2A1 4242/4885 |
| US-20240124514-A1 | DEOXYNUCLEOSIDE MODIFIED RUTHENIUM COMPLEX, AND PREPARATION METHOD AND USE THEREOF | RRM2B, RRM2, NCL | PDE5A 4441/4885AURKA 3963/4885SLC2A1 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.