Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.35 |
| ▸ | FNTB | P49356 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17172433 | 0.74 | CA1 (0.34) | MAPTCA1CA2CA4PTPN1 | |
| SCHEMBL13588527 | 0.65 | DHODH (0.40) | DHODH | |
| SCHEMBL12586186 | 0.65 | DHODH (0.40) | DHODH | |
| SCHEMBL7825318 | 0.65 | DHODH (0.31) | DHODH | |
| SCHEMBL23255527 | 0.64 | — | — | |
| SCHEMBL20269335 | 0.64 | — | — | |
| SCHEMBL7751403 | 0.63 | TLR4 (0.36) | MAPT | |
| SCHEMBL7751451 | 0.63 | CYP3A4 (0.35) | MAPTCA1CA2CA4PTPN1 | |
| SCHEMBL24483544 | 0.62 | ALDH1A1 (0.31) | MAPT | |
| SCHEMBL4581819 | 0.61 | CYP3A4 (0.33) | MAPTCA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10377733-B1 | Antimicrobials from an epigenetics based fungal metabolite screening program | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-08-13 | — | — | US | disclosed |
| US-10358431-B1 | Antimicrobials from an epigenetics based fungal metabolite screening program | UNIVERSITY OF SOUTH FLORIDA (US) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358431-B1 | Antimicrobials from an epigenetics based fungal metabolite screening program | HDAC7, HDAC9, HDAC4 | DHODH 302/4885FNTA 2796/4885FNTB 363/4885 |
| US-10377733-B1 | Antimicrobials from an epigenetics based fungal metabolite screening program | HDAC7, HDAC9, HDAC4 | DHODH 302/4885FNTA 2796/4885FNTB 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.