Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | CD81 | P60033 | 1/20 | 0.31 |
| ▸ | TLR4 | O00206 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2019347 | 0.78 | HSD11B1 (0.33) | TLR4HSD11B1 | |
| SCHEMBL27761884 | 0.65 | TLR4 (0.34) | TLR4HSD11B1 | |
| SCHEMBL190832 | 0.65 | TLR4 (0.34) | TLR4HSD11B1 | |
| SCHEMBL27771250 | 0.65 | TLR4 (0.34) | TLR4HSD11B1 | |
| SCHEMBL21180302 | 0.65 | DHODH (0.37) | DHODH | |
| SCHEMBL6350703 | 0.61 | SLC1A2 (0.37) | HSD11B1 | |
| SCHEMBL2017466 | 0.61 | SLC1A2 (0.34) | HSD11B1 | |
| SCHEMBL2017042 | 0.61 | SLC1A2 (0.34) | HSD11B1 | |
| SCHEMBL7003944 | 0.60 | CYP2C19 (0.35) | — | |
| SCHEMBL7994230 | 0.60 | SLC1A2 (0.37) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |