Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.51 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | PTGES | O14684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14579767 | 0.92 | MAP4K4 (0.47) | ADORA3MAP4K4PIM1CSNK1DCSNK2A1 | |
| SCHEMBL28647943 | 0.88 | MAP4K4 (0.50) | ADORA3MAP4K4PIM1CSNK1DCSNK2A1 | |
| SCHEMBL29922981 | 0.88 | MAP4K4 (0.50) | ADORA3MAP4K4PIM1CSNK1DCSNK2A1 | |
| SCHEMBL5323937 | 0.88 | MAP4K4 (0.52) | ADORA3MAP4K4PIM1CSNK1DCSNK2A1 | |
| SCHEMBL30171053 | 0.88 | MAP4K4 (0.52) | ADORA3MAP4K4PIM1CSNK1DCSNK2A1 | |
| SCHEMBL17368965 | 0.86 | PARP1 (0.42) | ADORA3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2062423 | 0.85 | TNKS (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL31249853 | 0.85 | PARP1 (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL18574377 | 0.85 | TNKS (0.48) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL12676130 | 0.85 | PARP1 (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10358455-B2 | Arene ruthenium complex, preparation method and utilization thereof | GUANGDONG PHARMACEUTICAL UNIVERSITY (CN) | 2019-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10358455-B2 | Arene ruthenium complex, preparation method and utilization thereof | CBR3, CBR1, C1R | ADORA3 422/4885MAP4K4 3953/4885PIM1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.