SCHEMBL5323937

SCHEMBL5323937

c1ccc(-c2nc3c4cccnc4c4ncccc4c3[nH]2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAP4K4 O95819 1/20 0.52
PIM1 P11309 1/20 0.52
CSNK1D P48730 1/20 0.52
CSNK2A1 P68400 1/20 0.52
DYRK1A Q13627 1/20 0.52
PIM3 Q86V86 1/20 0.52
CLK4 Q9HAZ1 1/20 0.52
ADORA3 P0DMS8 1/20 0.46
ALDH1A1 P00352 4/20 0.46
POLB P06746 3/20 0.46
KDM4E B2RXH2 3/20 0.46
MEN1 O00255 3/20 0.46
MAPT P10636 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HPGD P15428 2/20 0.46
HTT P42858 2/20 0.46
TNKS O95271 3/20 0.44
PARP1 P09874 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30171053 1.00 MAP4K4 (0.52) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL29922981 0.97 MAP4K4 (0.50) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL28647943 0.97 MAP4K4 (0.50) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL14579767 0.95 MAP4K4 (0.47) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL28296998 0.90 NOX1 (0.45) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL17793421 0.90 ALDH1A1 (0.48) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL30496134 0.90 ALDH1A1 (0.48) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL30320785 0.90 NOX1 (0.44) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL17793419 0.88 NPC1 (0.56) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A
SCHEMBL2062423 0.88 TNKS (0.49) MAP4K4PIM1CSNK1DCSNK2A1DYRK1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109796503-A A kind of preparation method of double-core cyclopentadienyl type ruthenium complex and its application in antitumor 云南大学 2019-05-24 CN claimed
CN-115746028-A Fluorescent rare earth complex and preparation method and application thereof 华南师范大学 2023-03-07 CN disclosed
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
CN-109796503-A A kind of preparation method of double-core cyclopentadienyl type ruthenium complex and its application in antitumor 云南大学 2019-05-24 CN disclosed
WO-2017146420-A1 LED PACKAGE COMPRISING RED ORGANIC-INORGANIC HYBRID LIGHT-EMITTING MATERIAL AND BACKLIGHT UNIT EMPLOYING SAME 주식회사 효성 2017-08-31 WO disclosed
WO-2017138765-A1 LED LIGHT EMITTING DEVICE COMPRISING RED ORGANIC-INORGANIC COMPOSITE LIGHT EMITTING MATERIAL 주식회사 효성 2017-08-17 WO disclosed
WO-2017138764-A1 RED ORGANIC-INORGANIC COMPOSITE LIGHT EMITTING MATERIAL AND METHOD FOR PRODUCING SAME 주식회사 효성 2017-08-17 WO disclosed
WO-2007006026-A1 COMPOSITIONS AND USE THEREOF IN DYE SENSITIZED SOLAR CELLS GENERAL ELECTRIC COMPANY (US) 2007-01-11 WO disclosed
US-20070000539-A1 Compositions and use thereof in dye sensitized solar cells GENERAL ELECTRIC COMPANY 2007-01-04 US disclosed
US-20070000539-A1 Compositions and use thereof in dye sensitized solar cells GENERAL ELECTRIC COMPANY 2007-01-04 US disclosed