Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | PIM1 | P11309 | 1/20 | 0.50 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.50 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.50 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.50 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28647943 | 1.00 | MAP4K4 (0.50) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL30171053 | 0.97 | MAP4K4 (0.52) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL5323937 | 0.97 | MAP4K4 (0.52) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL14579767 | 0.95 | MAP4K4 (0.47) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL31249853 | 0.88 | PARP1 (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL21180306 | 0.88 | ADORA3 (0.51) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL18574377 | 0.88 | TNKS (0.48) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL2062423 | 0.88 | TNKS (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL12676130 | 0.88 | PARP1 (0.49) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A | |
| SCHEMBL17793419 | 0.88 | NPC1 (0.56) | MAP4K4PIM1CSNK1DCSNK2A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113512069-B | Iridium (III) polypyridine composite liposome and application thereof in antitumor drugs | 广州市第一人民医院（广州消化疾病中心、广州医科大学附属市一人民医院、华南理工大学附属第二医院） | 2022-10-14 | — | — | CN | disclosed |