Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15946239 | 0.86 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180638 | 0.83 | MAPT (0.34) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL15946243 | 0.82 | KDM4E (0.39) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180601 | 0.81 | KDM4E (0.34) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180679 | 0.80 | SIRT2 (0.37) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL21180535 | 0.78 | AHR (0.37) | KDM4ESMN1; SMN2 | |
| SCHEMBL21180669 | 0.78 | BTK (0.36) | KDM4ELMNASMN1; SMN2 | |
| SCHEMBL21180563 | 0.77 | SIRT2 (0.33) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL20706786 | 0.76 | KDM4E (0.44) | KDM4EATML3MBTL1SIRT2SIRT1 | |
| SCHEMBL20706805 | 0.74 | KDM4E (0.50) | KDM4EATML3MBTL1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10361380-B2 | Heterocyclic compound and organic light-emitting device including the same | SAMSUNG DISPLAY CO., LTD. (KR) | 2019-07-23 | — | — | US | disclosed |