SCHEMBL21180625

SCHEMBL21180625

c1ccc2c(-c3cc4cc5c(cc4c4nnccc34)sc3ccccc35)csc2c1

nearest known ligand 0.33

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
POLB P06746 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
PTGIR P43119 1/20 0.32
BACE1 P56817 1/20 0.31
C1S P09871 1/20 0.31
ERN1 O75460 1/20 0.30
APP P05067 1/20 0.30
ACVRL1 P37023 1/20 0.30
ACVR1 Q04771 1/20 0.30
CDC7 O00311 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21180672 0.85 ALDH1A1 (0.35) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL14725757 0.79 GPR3 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL16520889 0.79 KDM4E (0.36) ALDH1A1HPGDL3MBTL1APP
SCHEMBL16472922 0.77 GPR3 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21180615 0.74 CYP11B1 (0.48) RAB9A
SCHEMBL21180655 0.74 MAPT (0.35) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21180639 0.74 ALDH1A1 (0.38) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21180547 0.73 ALDH1A1 (0.35) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL16472876 0.72 GPR3 (0.34) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21180627 0.70 ALDH1A1 (0.34) GPR3ALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361380-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed