SCHEMBL21180647

SCHEMBL21180647

c1ccc2cc(-c3cc4ccccc4c4cc5sc6ccccc6c5cc34)ccc2c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSTP1 P09211 1/20 0.40
GPR84 Q9NQS5 1/20 0.40
GPR3 P46089 1/20 0.40
ALOX5 P09917 2/20 0.40
S1PR5 Q9H228 8/20 0.39
S1PR4 O95977 6/20 0.39
ALDH1A1 P00352 4/20 0.38
MAPT P10636 2/20 0.38
HPGD P15428 2/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
POLB P06746 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
CYP11B1 P15538 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
HDAC4 P56524 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21180649 0.91 ALDH1A1 (0.44) GPR3ALOX5ALDH1A1MAPTHPGD
SCHEMBL21180621 0.91 ALDH1A1 (0.44) GPR3ALOX5ALDH1A1MAPTHPGD
SCHEMBL21180588 0.91 GPR3 (0.42) GPR3ALOX5ALDH1A1MAPTHPGD
SCHEMBL21180620 0.87 GPR3 (0.44) GPR84GPR3ALOX5ALDH1A1MAPT
SCHEMBL22155461 0.86 ALDH1A1 (0.41) GPR3ALOX5ALDH1A1MAPTHPGD
SCHEMBL18907451 0.84 GPR3 (0.44) GSTP1GPR84GPR3ALOX5S1PR5
SCHEMBL14725769 0.84 GPR3 (0.44) GPR3ALOX5ALDH1A1MAPTHPGD
SCHEMBL18907484 0.84 ALDH1A1 (0.45) GSTP1GPR84GPR3ALOX5S1PR5
SCHEMBL24362868 0.82 ALDH1A1 (0.44) GSTP1GPR3ALOX5S1PR5S1PR4
SCHEMBL21180586 0.82 MAPT (0.36) GPR3ALOX5ALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10361380-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2019-07-23 US disclosed