Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7703503 | 0.81 | FFAR4 (0.45) | ALDH1A1FFAR4PLA2G2AKDM4EGAA | |
| SCHEMBL12489097 | 0.81 | FFAR4 (0.47) | ALDH1A1FFAR4PLA2G2AKDM4EGAA | |
| SCHEMBL16958853 | 0.80 | SLC6A4 (0.49) | ALDH1A1FFAR4PLA2G2AKDM4EGAA | |
| SCHEMBL364074 | 0.78 | FFAR4 (0.48) | ALDH1A1FFAR4PLA2G2AKDM4EGAA | |
| SCHEMBL2775033 | 0.76 | FFAR4 (0.43) | ALDH1A1FFAR4PLA2G2AKDM4EGAA | |
| Bromide SCHEMBL17714327 | 0.75 | PLA2G2A (0.46) | ALDH1A1FFAR4PLA2G2AKDM4ESLC6A4 | |
| SCHEMBL17006136 | 0.75 | FFAR4 (0.42) | ALDH1A1FFAR4PLA2G2AKDM4ESLC6A4 | |
| SCHEMBL7696307 | 0.73 | ALDH1A1 (0.43) | ALDH1A1FFAR4PLA2G2AKDM4ESLC6A4 | |
| SCHEMBL1741537 | 0.73 | PLA2G2A (0.52) | ALDH1A1FFAR4PLA2G2ASLC6A4SLC6A3 | |
| SCHEMBL2708451 | 0.73 | SLC6A4 (0.51) | ALDH1A1FFAR4PLA2G2AKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221304-B1 | NOVEL CARBOXYLIC ACID COMPOUNDS USEFUL FOR INHIBITING MICROSOMAL PROSTAGLANDIN E2 SYNTHASE-1 | LILLY CO ELI (US) | 2019-07-24 | — | — | EP | disclosed |