Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.40 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117210 | 0.91 | MAPT (0.42) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2118300 | 0.87 | MAPT (0.48) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2118441 | 0.87 | MAPT (0.43) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2119232 | 0.86 | MAPT (0.45) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2117812 | 0.85 | MAPT (0.48) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2120161 | 0.84 | MAPT (0.54) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2117725 | 0.84 | GHSR (0.41) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2117841 | 0.84 | MAPT (0.54) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2117419 | 0.84 | USP2 (0.42) | MAPTALDH1A1CYP2C9TSHRNPSR1 | |
| SCHEMBL2119462 | 0.84 | LMNA (0.55) | MAPTALDH1A1CYP2C9TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095012-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1A, HIF1AN, EGLN3 | MAPT 4747/4885ALDH1A1 1063/4885CYP2C9 2049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.