Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617845 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617765 | 1.00 | KMT2A (0.51) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2120688 | 0.92 | MEN1 (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617888 | 0.92 | MEN1 (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617814 | 0.92 | MEN1 (0.45) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617759 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2119316 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617831 | 0.88 | KMT2A (0.49) | KMT2AALDH1A1MEN1SMN1; SMN2MAPT | |
| SCHEMBL2617763 | 0.87 | SERPINE1 (0.49) | KMT2AMEN1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2118277 | 0.87 | SERPINE1 (0.49) | KMT2AMEN1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507474-B2 | Anthelmintic agents and their use | INTERVET INTERNATIONAL B.V. (NL) | 2013-08-13 | — | — | US | disclosed |
| US-20120094981-A1 | ANTHELMINTIC AGENTS AND THEIR USE | INTERVET INTERNATIONAL B.V. (NL) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120094981-A1 | ANTHELMINTIC AGENTS AND THEIR USE | ABCB11, ACHE, CMA1 | KMT2A 2602/4885ALDH1A1 331/4885MEN1 1277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.