SCHEMBL21183007

SCHEMBL21183007

C=C/C=C\c1cc(N)ccc1N

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 2/20 0.32
APP P05067 1/20 0.32
ALDH1A1 P00352 3/20 0.31
TDP1 Q9NUW8 2/20 0.31
CYP3A4 P08684 2/20 0.31
ALOX15 P16050 2/20 0.31
THRB P10828 2/20 0.31
PKM P14618 2/20 0.31
RECQL P46063 2/20 0.31
CYP19A1 P11511 2/20 0.31
MEN1 O00255 1/20 0.31
USP2 O75604 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
APEX1 P27695 1/20 0.31
BLM P54132 1/20 0.31
KMT2A Q03164 1/20 0.31
MCL1 Q07820 1/20 0.31
HTR6 P50406 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18059380 0.83 CASP1 (0.37) CASP1APPALDH1A1TDP1RECQL
SCHEMBL23992578 0.80 ALDH1A1 (0.45) CASP1APPALDH1A1TDP1CYP3A4
SCHEMBL16130316 0.80 TDP1 (0.45) ALDH1A1TDP1CYP3A4ALOX15THRB
SCHEMBL3480852 0.78 CASP1 (0.37) CASP1ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL23863464 0.76 ALDH1A1 (0.45) CASP1ALDH1A1CYP3A4ALOX15THRB
SCHEMBL454407 0.74 CASP1 (0.39) CASP1ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL454405 0.74 CASP1 (0.39) CASP1ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL6344325 0.74 CYP3A4 (0.39) CASP1ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL10203130 0.74 CYP3A4 (0.39) CASP1ALDH1A1TDP1CYP3A4ALOX15
SCHEMBL1374281 0.74 CYP3A4 (0.39) CASP1ALDH1A1TDP1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3514163-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2019-07-24 EP disclosed