Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.31 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.31 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.31 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.31 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.31 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.31 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.31 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607789 | 0.91 | THRB (0.45) | THRBSCN9AGRM2ERN1PRKAB2 | |
| SCHEMBL21183107 | 0.90 | THRB (0.38) | THRBERN1ESR1ESR2APP | |
| SCHEMBL18432985 | 0.86 | ESR1 (0.34) | THRBERN1ESR1ESR2FFAR4 | |
| SCHEMBL21475263 | 0.85 | THRB (0.38) | THRBESR1ESR2APPCYP2C19 | |
| SCHEMBL23045942 | 0.83 | THRB (0.43) | THRB | |
| SCHEMBL19157824 | 0.83 | ERN1 (0.46) | THRBGRM2ERN1PRKAB2PRKAG1 | |
| SCHEMBL18436317 | 0.82 | THRB (0.39) | THRBSCN9AGRM2ERN1PRKAB2 | |
| SCHEMBL9607903 | 0.81 | THRB (0.44) | THRBERN1ESR1ESR2APP | |
| SCHEMBL21592059 | 0.81 | THRB (0.41) | THRBCYP2C19 | |
| SCHEMBL9607850 | 0.80 | THRB (0.43) | THRBERN1ESR1ESR2APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112440-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |