SCHEMBL9607789

SCHEMBL9607789

C=CC(=O)Oc1ccc(-c2ccc(OC(=O)C=C)cc2F)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.45
ERN1 O75460 1/20 0.35
GRM2 Q14416 1/20 0.35
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
PRKAB2 O43741 2/20 0.35
PRKAG1 P54619 2/20 0.35
PRKAA2 P54646 2/20 0.35
PRKAA1 Q13131 2/20 0.35
PRKAG3 Q9UGI9 2/20 0.35
PRKAG2 Q9UGJ0 2/20 0.35
PRKAB1 Q9Y478 2/20 0.35
PRKCZ Q05513 1/20 0.35
FFAR4 Q5NUL3 2/20 0.34
APP P05067 1/20 0.34
CYP2C19 P33261 1/20 0.34
SCN9A Q15858 1/20 0.34
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19157824 0.92 ERN1 (0.46) THRBERN1GRM2PRKAB2PRKAG1
SCHEMBL23045942 0.92 THRB (0.43) THRBKDM4EMEN1TP53CYP3A4
SCHEMBL21183104 0.91 THRB (0.39) THRBERN1GRM2ESR1ESR2
SCHEMBL18436317 0.91 THRB (0.39) THRBERN1GRM2ESR1ESR2
SCHEMBL9607903 0.90 THRB (0.44) THRBERN1ESR1ESR2APP
SCHEMBL9607850 0.89 THRB (0.43) THRBERN1ESR1ESR2APP
SCHEMBL18522597 0.88 THRB (0.37) THRBERN1GRM2PRKAB2PRKAG1
SCHEMBL17549965 0.88 ELANE (0.42) THRBERN1GRM2PRKAB2PRKAG1
SCHEMBL18646584 0.88 MEN1 (0.48) THRBKDM4EMEN1ALDH1A1MAPT
SCHEMBL23544535 0.88 THRB (0.40) THRBERN1GRM2PRKAB2PRKAG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 503 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-12043781-B2 Liquid-crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
EP-4400561-A1 LIQUID-CRYSTAL MEDIUM Merck Patent GmbH (DE) 2024-07-17 EP disclosed
WO-2024132893-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024133363-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2024-06-27 WO disclosed
WO-2024126567-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2024-06-20 WO disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
US-20240067879-A1 Liquid-crystal medium MERCK PATENT GMBH (DE) 2024-02-29 US disclosed
EP-3924447-B1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2024-01-24 EP disclosed
EP-4306614-A1 LIQUID-CRYSTALLINE MEDIUM Merck Patent GmbH (DE) 2024-01-17 EP disclosed
EP-2557140-A2 Liquid-crystalline medium Merck Patent GmbH (DE) 2013-02-13 EP disclosed
WO-2012130380-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-10-04 WO disclosed
WO-2012126562-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-09-27 WO disclosed
WO-2012097858-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2012-07-26 WO disclosed
WO-2012079710-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-21 WO disclosed
WO-2012072201-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-06-07 WO disclosed
WO-2012069151-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2012-05-31 WO disclosed
EP-2457975-A2 Liquid-crystalline mixtures Merck Patent GmbH (DE) 2012-05-30 EP disclosed
US-20100033662-A1 LIQUID CRYSTAL DISPLAY SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-11 US disclosed
US-20100033662-A1 LIQUID CRYSTAL DISPLAY SAMSUNG ELECTRONICS CO., LTD. (KR) 2010-02-11 US disclosed