Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25944979 | 0.96 | ERN1 (0.37) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL9607788 | 0.94 | CFD (0.42) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL17433322 | 0.92 | CFD (0.41) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL25944835 | 0.92 | ERN1 (0.43) | FFAR1ERN1LMNAMAPK1HTT | |
| SCHEMBL25944784 | 0.91 | ELANE (0.41) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL15385612 | 0.89 | ERN1 (0.40) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL18472702 | 0.89 | CFD (0.50) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL21183112 | 0.88 | CFD (0.36) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL2604650 | 0.88 | ELANE (0.39) | CFDFFAR1ERN1ELANELMNA | |
| SCHEMBL18869421 | 0.88 | ERN1 (0.49) | FFAR1ERN1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112440-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-07-24 | — | — | EP | disclosed |