Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | RARA | P10276 | 1/20 | 0.34 |
| ▸ | RARB | P10826 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607907 | 0.93 | ELANE (0.48) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL19824549 | 0.93 | ELANE (0.48) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL21183111 | 0.91 | CFD (0.38) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL18699653 | 0.90 | ABCB1 (0.47) | ELANEABCB1FFAR1PPARDBACE1 | |
| SCHEMBL17433322 | 0.90 | CFD (0.41) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL9607788 | 0.88 | CFD (0.42) | ELANEKMT2AATMFFAR1LMNA | |
| SCHEMBL21183099 | 0.88 | ELANE (0.42) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL25944979 | 0.87 | ERN1 (0.37) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL21469976 | 0.86 | THRB (0.40) | ELANEKMT2AATMABCB1FFAR1 | |
| SCHEMBL17433294 | 0.86 | THRB (0.40) | ELANEKMT2AATMABCB1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4056667-B1 | LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERIZABLE COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-08-02 | — | — | EP | disclosed |