Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MDM4 | O15151 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18720480 | 0.79 | HDAC4 (0.42) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL21183163 | 0.77 | HDAC4 (0.38) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL683932 | 0.77 | CYP3A4 (0.44) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL576332 | 0.73 | HPGD (0.55) | ALDH1A1HPGDMAPTSMN1; SMN2TDP1 | |
| SCHEMBL374780 | 0.72 | HDAC4 (0.56) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL22561859 | 0.72 | MCL1 (0.50) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL21102636 | 0.72 | CYP3A4 (0.40) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL14199938 | 0.72 | ALDH1A1 (0.40) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL12461692 | 0.72 | PTGS2 (0.49) | HDAC4HDAC8ALDH1A1ALOX12HTT | |
| SCHEMBL20072439 | 0.72 | HDAC4 (0.46) | HDAC4HDAC8ALDH1A1ALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3152216-B1 | BICYCLIC COMPOUNDS AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2019-07-24 | — | — | EP | disclosed |