Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.62 |
| ▸ | MERTK | Q12866 | 2/20 | 0.62 |
| ▸ | PIK3CD | O00329 | 18/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14752198 | 0.90 | AXL (0.71) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL30590258 | 0.90 | AXL (0.71) | AXLMERTKPIK3CDKCNH2 | |
| Trifluoroacetic Acid SCHEMBL14736623 | 0.85 | PIK3CD (0.65) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL29836131 | 0.85 | PIK3CD (0.71) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL14737302 | 0.85 | PIK3CD (0.71) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL14736877 | 0.84 | AXL (0.75) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL14736418 | 0.83 | AXL (0.81) | AXLMERTKPIK3CD | |
| SCHEMBL14736612 | 0.83 | AXL (0.88) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL31367086 | 0.83 | PIK3CD (0.72) | AXLMERTKPIK3CDKCNH2 | |
| SCHEMBL23893256 | 0.82 | PIK3CD (0.61) | AXLMERTKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513793-A1 | HETEROCYCLYLAMINES AS PI3K INHIBITORS | Incyte Holdings Corporation (US) | 2019-07-24 | — | — | EP | disclosed |