Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | BRD1 | O95696 | 1/20 | 0.50 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.50 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.50 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.50 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.50 |
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2117837 | 0.89 | STAT3 (0.60) | HSD11B1DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL2119549 | 0.84 | MAPT (0.46) | HSD11B1TP53KMT2AMAPTPOLB | |
| SCHEMBL6555449 | 0.84 | KDM1A (0.68) | TP53THRBKDM1ABRD4BRD1 | |
| SCHEMBL2119740 | 0.83 | FFAR4 (0.48) | HSD11B1TP53KMT2AMAPTPOLB | |
| SCHEMBL2117287 | 0.83 | KDM1A (0.51) | HSD11B1IDO1TP53THRBKDM1A | |
| SCHEMBL2118454 | 0.81 | HSD11B1 (0.51) | HSD11B1DRD2HTR2AHTR2CDRD3 | |
| SCHEMBL2118647 | 0.81 | PIK3CB (0.50) | HSD11B1TP53KMT2AMAPTPOLB | |
| SCHEMBL2118170 | 0.81 | MAPT (0.45) | HSD11B1TP53KMT2AMAPTPOLB | |
| SCHEMBL2118637 | 0.81 | TUBB4A (0.51) | HSD11B1TP53MAPT | |
| SCHEMBL2119979 | 0.80 | ALDH1A1 (0.47) | HSD11B1TP53KMT2AMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | ELARA PHARMACEUTICALS GMBH (DE) | 2012-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120095024-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE | HIF1AN, HIF1A, EGLN2 | HSD11B1 3280/4885DRD2 4207/4885HTR2A 2874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.