SCHEMBL211842

SCHEMBL211842

CCCCc1cc(CCCC)c(O)c(C(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.53
AKR1C2 P52895 1/20 0.52
AKR1C1 Q04828 1/20 0.52
PPARA Q07869 2/20 0.49
GABRP O00591 1/20 0.48
GABRD O14764 1/20 0.48
GABRA1 P14867 1/20 0.48
GABRB1 P18505 1/20 0.48
GABRG2 P18507 1/20 0.48
GABRB3 P28472 1/20 0.48
GABRA5 P31644 1/20 0.48
GABRA3 P34903 1/20 0.48
GABRA2 P47869 1/20 0.48
GABRB2 P47870 1/20 0.48
GABRA4 P48169 1/20 0.48
GABRE P78334 1/20 0.48
GABRA6 Q16445 1/20 0.48
GABRG1 Q8N1C3 1/20 0.48
GABRG3 Q99928 1/20 0.48
GABRQ Q9UN88 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11477238 0.98 KAT8 (0.51) KAT8AKR1C2AKR1C1PPARAGABRP
SCHEMBL9133047 0.98 KAT8 (0.51) KAT8AKR1C2AKR1C1PPARAGABRP
SCHEMBL11478526 0.98 KAT8 (0.51) KAT8AKR1C2AKR1C1PPARAGABRP
SCHEMBL11477241 0.98 KAT8 (0.51) KAT8AKR1C2AKR1C1PPARAGABRP
SCHEMBL9133045 0.98 KAT8 (0.51) KAT8AKR1C2AKR1C1PPARAGABRP
SCHEMBL8981485 0.95 KAT8 (0.59) KAT8AKR1C2AKR1C1PPARAPTPN1
SCHEMBL7780121 0.94 KAT8 (0.61) KAT8AKR1C2AKR1C1PPARARARB
SCHEMBL9955366 0.94 KAT8 (0.61) KAT8AKR1C2AKR1C1PPARARARB
SCHEMBL9303706 0.94 KAT8 (0.61) KAT8AKR1C2AKR1C1PPARARARB
SCHEMBL3220998 0.94 KAT8 (0.61) KAT8AKR1C2AKR1C1PPARARARB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-55028847-A None JP disclosed
EP-3707242-B1 COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS UNIV KOELN (DE) 2022-05-18 EP disclosed
US-20200339502-A1 COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS UNIVERSITÄT ZU KÖLN (DE) 2020-10-29 US disclosed
EP-3480296-A1 DIAMINES FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS Universität zu Köln (DE) 2019-05-08 EP disclosed
US-10188754-B2 Compositions and methods for chemical exchange saturation transfer (CEST) based magnetic resonance imaging (MRI) THE JOHNS HOPKINS UNIVERSITY (US) 2019-01-29 US disclosed
EP-1871844-B1 BUBBLE COMPOSITION WITH COLOR CHANGING INDICATOR C2C TECHNOLOGIES LLC (US) 2014-08-27 EP disclosed
EP-1890194-B1 Toner RICOH CO LTD (JP) 2013-01-23 EP disclosed
US-8088540-B2 Photoreceptor for electrophotography HODOGAYA CHEMICAL CO., LTD. (JP) 2012-01-03 US disclosed
CN-100465801-C Toner and method of forming image by utilizing such toner RICOH KK (JP) 2009-03-04 CN disclosed
US-20090011349-A1 Photoreceptor for Electrophotography HODOGAYA CHEMICAL CO., LTD. (JP) 2009-01-08 US disclosed
US-6964835-B2 Toner and image forming method using the toner RICOH COMPANY, LTD. (JP) 2005-11-15 US disclosed
US-20050175924-A1 TONER AND IMAGE FORMING METHOD USING THE TONER RICOH COMPANY, LTD. (JP) 2005-08-11 US disclosed
EP-1383011-B1 Toner comprising zirconium based organometallic charge control agent and image forming method RICOH KK (JP) 2005-04-06 EP disclosed
US-6852462-B2 Toner, method of forming the toner, and image forming method and apparatus using the toner RICOH COMPANY LIMITED (JP) 2005-02-08 US disclosed
CN-1480790-A Toner and method of forming image by utilizing such toner ������������ʽ���� 2004-03-10 CN disclosed
EP-1383011-A1 Toner comprising zirconium based organometallic charge control agent and image forming method Ricoh Company, Ltd. (JP) 2004-01-21 EP disclosed
EP-1308791-A1 Toner, method of forming the toner, and image forming method and apparatus using the toner Ricoh Company, Ltd. (JP) 2003-05-07 EP disclosed
US-5723250-A Process for image formation using liquid developer FUJI XEROX CO., LTD. (JP) 1998-03-03 US disclosed
EP-0015133-A2 Pressure sensitive copying system Mitsubishi Paper Mills, Ltd. (JP) 1980-09-03 EP disclosed
JP-S5528847-A RECORDING MATERIAL FUJI PHOTO FILM CO LTD 1980-02-29 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10188754-B2 Compositions and methods for chemical exchange saturation transfer (CEST) based magnetic resonance imaging (MRI) GART, SLC43A1, AADAT KAT8 1174/4885AKR1C2 779/4885AKR1C1 893/4885
US-20200339502-A1 COMPOUNDS FOR USE IN THE ELIMINATION OF PLURIPOTENT STEM CELLS ALPG, RARB, RARG KAT8 3537/4885AKR1C2 1822/4885AKR1C1 1791/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.