Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 11/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 10/20 | 0.75 |
| ▸ | MAPT | P10636 | 8/20 | 0.75 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.75 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.75 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.75 |
| ▸ | XDH | P47989 | 5/20 | 0.75 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.75 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.75 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.75 |
| ▸ | CA12 | O43570 | 4/20 | 0.75 |
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.75 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.75 |
| ▸ | BCHE | P06276 | 4/20 | 0.75 |
| ▸ | ACHE | P22303 | 4/20 | 0.75 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.75 |
| ▸ | PPARG | P37231 | 3/20 | 0.75 |
| ▸ | CA7 | P43166 | 3/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Galangin SCHEMBL7926038 | 0.94 | MEN1 (0.85) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Datiscetin SCHEMBL15675904 | 0.93 | MEN1 (0.75) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Kaempferol SCHEMBL31164054 | 0.93 | MEN1 (0.79) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Kaempferol SCHEMBL1485787 | 0.93 | MEN1 (0.79) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Myricetin SCHEMBL2278240 | 0.90 | MEN1 (0.77) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Kaempferol SCHEMBL731179 | 0.88 | MEN1 (0.68) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Quercetin SCHEMBL111510 | 0.88 | MEN1 (0.76) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Morin SCHEMBL6043175 | 0.87 | FTO (0.65) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Galangin SCHEMBL29393121 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP3A4MAPTABCB1 | |
| Galangin SCHEMBL117225 | 0.87 | MEN1 (1.00) | MEN1KMT2ACYP3A4MAPTABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008071416-A1 | MORIN, A NEW INHIBITOR OF MICROBIAL HYALURONATE LYASE | LEIBNIZ INSTITUTE FOR NATURAL PRODUCT RESEARCH AND INFECTION BIOLOGY E.V. HANS-KNÖLL-INSTITUT (HKI) (DE) | 2008-06-19 | — | — | WO | claimed |
| EP-1932526-A1 | Morin, a new inhibitor of microbial hyaluronate lyase | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut (DE) | 2008-06-18 | — | — | EP | claimed |
| US-20230123785-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2023-04-20 | — | — | US | disclosed |
| US-11549950-B2 | Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms | THE TRUSTEES OF PRINCETON UNIVERSITY | 2023-01-10 | — | — | US | disclosed |
| US-20210041452-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2021-02-11 | — | — | US | disclosed |
| EP-3662053-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | The Trustees of Princeton University (US) | 2020-06-10 | — | — | EP | disclosed |
| CN-111164202-A | Recessive metabolites and methods for activating silent biosynthetic gene clusters in a variety of microorganisms | 普林斯顿大学 | 2020-05-15 | — | — | CN | disclosed |
| WO-2019027877-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2019-02-07 | — | — | WO | disclosed |
| US-20150182472-A1 | DENATURED LACTOGLOBULIN AND POLYPHENOL COASSEMBLIES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION, LTD. (IL) | 2015-07-02 | — | — | US | disclosed |
| US-9005664-B2 | Denatured lactoglobulin and polyphenol coassemblies | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2015-04-14 | — | — | US | disclosed |
| US-20120093933-A1 | DENATURED LACTOGLOBULIN AND POLYPHENOL COASSEMBLIES | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2012-04-19 | — | — | US | disclosed |
| WO-2008071416-A1 | MORIN, A NEW INHIBITOR OF MICROBIAL HYALURONATE LYASE | LEIBNIZ INSTITUTE FOR NATURAL PRODUCT RESEARCH AND INFECTION BIOLOGY E.V. HANS-KNÖLL-INSTITUT (HKI) (DE) | 2008-06-19 | — | — | WO | disclosed |
| WO-2008071416-A1 | MORIN, A NEW INHIBITOR OF MICROBIAL HYALURONATE LYASE | LEIBNIZ INSTITUTE FOR NATURAL PRODUCT RESEARCH AND INFECTION BIOLOGY E.V. HANS-KNÖLL-INSTITUT (HKI) (DE) | 2008-06-19 | — | — | WO | disclosed |
| EP-1932526-A1 | Morin, a new inhibitor of microbial hyaluronate lyase | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1932526-A1 | Morin, a new inhibitor of microbial hyaluronate lyase | Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V. Hans-Knöll-Institut (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1100539-A2 | COMBINATION OF ACTIVE SUBSTANCES, ESPECIALLY FOR THE PROPHYLAXIS AND THERAPY OF ISCHAEMIC ORGANIC LESIONS AND REPERFUSION SYNDROMES | Vascular Biotech GmbH (DE) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000007578-A2 | COMBINATION OF ACTIVE SUBSTANCES, ESPECIALLY FOR THE PROPHYLAXIS AND THERAPY OF ISCHAEMIC ORGANIC LESIONS AND REPERFUSION SYNDROMES | VASCULAR BIOTECH GMBH (DE) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210041452-A1 | CRYPTIC METABOLITES AND METHOD FOR ACTIVATING SILENT BIOSYNTHETIC GENE CLUSTERS IN DIVERSE MICROORGANISMS | GLA, ERG28, SBK3 | MEN1 2842/4885KMT2A 1729/4885CYP3A4 524/4885 |
| US-11549950-B2 | Cryptic metabolites and method for activating silent biosynthetic gene clusters in diverse microorganisms | ERG28, SBK3, GLB1 | MEN1 2304/4885KMT2A 1924/4885CYP3A4 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.