Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29576319 | 1.00 | CYP4F2 (0.54) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL22684772 | 0.88 | CYP4F2 (0.46) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL22703692 | 0.85 | L3MBTL1 (0.43) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL23496632 | 0.85 | KMT2A (0.47) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL23501075 | 0.84 | CYP4F2 (0.55) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL29882204 | 0.84 | CYP4F2 (0.55) | CYP4F2CYP4A11L3MBTL1ALDH1A1NPC1 | |
| SCHEMBL3074145 | 0.82 | CYP4F2 (0.61) | CYP4F2CYP4A11ALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL20472328 | 0.82 | OPRK1 (0.48) | L3MBTL1ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL21185448 | 0.81 | TSHR (0.46) | L3MBTL1ALDH1A1NPC1SMN1; SMN2RAB9A | |
| SCHEMBL28603823 | 0.81 | CYP4F2 (0.52) | CYP4F2CYP4A11ALDH1A1NPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110041316-B | TAM family kinase/CSF 1R kinase inhibitors and uses thereof | 药捷安康(南京)科技股份有限公司 | 2022-04-19 | — | — | CN | disclosed |
| US-20210177828-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | TRANSTHERA SCIENCES (NANJING), INC. (CN) | 2021-06-17 | — | — | US | disclosed |
| EP-3741752-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2020-11-25 | — | — | EP | disclosed |
| EP-3741752-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | Nanjing Transthera Biosciences Co., Ltd. (CN) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019141202-A9 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-08-29 | — | — | WO | disclosed |
| WO-2019141202-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | 南京药捷安康生物科技有限公司 | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210177828-A1 | TAM FAMILY KINASE /AND CSF1R KINASE INHIBITOR AND USE THEREOF | CSF1R, CSF3R, FLT3 | CYP4F2 2898/4885CYP4A11 3101/4885L3MBTL1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.