Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL23R | Q5VWK5 | 16/20 | 0.63 |
| ▸ | CD47 | Q08722 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23913045 | 0.94 | CD47 (0.65) | IL23RCD47 | |
| SCHEMBL21185972 | 0.93 | IL23R (0.65) | IL23R | |
| SCHEMBL29353777 | 0.91 | CD47 (0.69) | IL23RCD47 | |
| SCHEMBL24172455 | 0.91 | CD47 (0.69) | IL23RCD47 | |
| SCHEMBL19731206 | 0.90 | IL23R (0.61) | IL23RCD47 | |
| SCHEMBL24172454 | 0.90 | IL23R (0.61) | IL23RCD47 | |
| SCHEMBL19731216 | 0.90 | IL23R (0.61) | IL23RCD47 | |
| SCHEMBL16692898 | 0.90 | IL23R (0.61) | IL23RCD47 | |
| SCHEMBL16692892 | 0.90 | IL23R (0.61) | IL23RCD47 | |
| SCHEMBL16692899 | 0.90 | IL23R (0.61) | IL23RCD47 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225649-A1 | AGENTS THAT ACTIVATE CD47 AND THEIR USE IN THE TREATMENT OF INFLAMMATION | SORBONNE UNIVERSITE (FR) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225649-A1 | AGENTS THAT ACTIVATE CD47 AND THEIR USE IN THE TREATMENT OF INFLAMMATION | CD47, LGALS2, LGALS1 | IL23R 1296/4885CD47 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.