SCHEMBL23913045

SCHEMBL23913045

CCCC[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(=N)N)N(C)C(=O)[C@H](N)CCCCN)C(C)C)C(C)C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CCCCN)C(N)=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CD47 Q08722 1/20 0.65
IL23R Q5VWK5 16/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29353777 0.97 CD47 (0.69) CD47IL23R
SCHEMBL24172455 0.97 CD47 (0.69) CD47IL23R
SCHEMBL21185976 0.94 IL23R (0.63) CD47IL23R
SCHEMBL21185972 0.86 IL23R (0.65) IL23R
SCHEMBL30092992 0.85 IL23R (0.62) CD47IL23R
SCHEMBL30092995 0.85 IL23R (0.62) CD47IL23R
Polyphemusin I SCHEMBL30507731 0.84 IL23R (0.76) IL23R
SCHEMBL29551233 0.84 GHSR (0.55) CD47IL23R
SCHEMBL30092985 0.84 IL23R (0.63) CD47IL23R
SCHEMBL30786423 0.83 GHSR (0.62) IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11142548-B2 Agents that activate CD47 and their use in the treatment of inflammation SORBONNE UNIVERSITE (FR) 2021-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11142548-B2 Agents that activate CD47 and their use in the treatment of inflammation CD47, LGALS2, LGALS1 CD47 1/4885IL23R 1296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.