Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 2/20 | 0.57 |
| ▸ | BRAF | P15056 | 2/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | TEK | Q02763 | 1/20 | 0.51 |
| ▸ | SCD | O00767 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | NCS1 | P62166 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186052 | 0.91 | RAF1 (0.53) | RAF1BRAFKCNH2CSNK1DKDR | |
| SCHEMBL21186063 | 0.90 | RAF1 (0.56) | RAF1BRAFKCNH2CSNK1DSCD | |
| SCHEMBL21186101 | 0.90 | NPC1 (0.60) | RAF1BRAFKCNH2SCDMEN1 | |
| SCHEMBL21186130 | 0.89 | NPC1 (0.52) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21186156 | 0.89 | MAPT (0.59) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21186175 | 0.88 | DCLK1 (0.56) | RAF1BRAFCSNK1DSCDMEN1 | |
| SCHEMBL21186151 | 0.88 | NPC1 (0.54) | RAF1BRAFKCNH2SCDMEN1 | |
| SCHEMBL21186181 | 0.87 | MET (0.51) | RAF1BRAFKCNH2CSNK1DSCD | |
| SCHEMBL21186165 | 0.87 | NPC1 (0.64) | SCDMEN1NPC1RAB9AKMT2A | |
| SCHEMBL21186168 | 0.86 | DCLK1 (0.53) | RAF1BRAFCSNK1DSCDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |