Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.60 |
| ▸ | RAB9A | P51151 | 10/20 | 0.60 |
| ▸ | MEN1 | O00255 | 6/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SCD | O00767 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | RAF1 | P04049 | 1/20 | 0.49 |
| ▸ | BRAF | P15056 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186151 | 0.94 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186256 | 0.92 | SCD (0.53) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186130 | 0.92 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186156 | 0.92 | MAPT (0.59) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186167 | 0.91 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186183 | 0.91 | NPC1 (0.54) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186046 | 0.91 | MAPK1 (0.56) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186175 | 0.91 | DCLK1 (0.56) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL21186154 | 0.90 | MET (0.56) | NPC1RAB9AMEN1KMT2ASCD | |
| SCHEMBL30098848 | 0.90 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2ASCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |