Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | RAB9A | P51151 | 10/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | SCD | O00767 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186183 | 0.93 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186252 | 0.92 | NPC1 (0.58) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186106 | 0.92 | NPC1 (0.52) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL30098848 | 0.92 | NPC1 (0.52) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186176 | 0.92 | DCLK1 (0.54) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186101 | 0.91 | NPC1 (0.60) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186256 | 0.89 | SCD (0.53) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186151 | 0.89 | NPC1 (0.54) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186154 | 0.88 | MET (0.56) | NPC1RAB9AKMT2AMEN1SCD | |
| SCHEMBL21186165 | 0.86 | NPC1 (0.64) | NPC1RAB9AKMT2AMEN1SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |