Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 13/20 | 0.61 |
| ▸ | RAB9A | P51151 | 12/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.61 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.60 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.60 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.55 |
| ▸ | SCD | O00767 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186165 | 0.92 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2DYRK1ATP53 | |
| SCHEMBL21186114 | 0.90 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2DYRK1ATP53 | |
| SCHEMBL21186171 | 0.84 | NPC1 (0.62) | NPC1RAB9ASMN1; SMN2DYRK1ATP53 | |
| SCHEMBL21186163 | 0.84 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL21186046 | 0.83 | MAPK1 (0.56) | NPC1RAB9ASMN1; SMN2TP53SCD | |
| SCHEMBL21186164 | 0.83 | RORC (0.46) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL21186130 | 0.82 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2DYRK1ATP53 | |
| SCHEMBL21186113 | 0.82 | MET (0.52) | NPC1RAB9APKMKLF5SCD | |
| SCHEMBL21186154 | 0.82 | MET (0.56) | NPC1RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL21186156 | 0.82 | MAPT (0.59) | NPC1RAB9ASMN1; SMN2TP53SCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |