Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186002 | 0.87 | KMT2A (0.64) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21186199 | 0.83 | NPC1 (0.59) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21186170 | 0.80 | NPC1 (0.51) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21186198 | 0.79 | NPC1 (0.49) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL23607120 | 0.77 | TOP1 (0.61) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL21186171 | 0.74 | NPC1 (0.62) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL22130324 | 0.72 | NPC1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL31219257 | 0.72 | NPC1 (0.53) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21186162 | 0.71 | MAPT (0.48) | NPC1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL21186275 | 0.70 | PIK3CG (0.62) | NPC1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |