Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | RORC | P51449 | 1/20 | 0.58 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186198 | 0.87 | NPC1 (0.49) | NPC1RAB9ARORCRIPK1MAPT | |
| SCHEMBL21186157 | 0.86 | NPC1 (0.48) | NPC1RAB9ARORCRIPK1MAPT | |
| SCHEMBL21186002 | 0.86 | KMT2A (0.64) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL21186147 | 0.83 | NPC1 (0.55) | NPC1RAB9AMAPTALDH1A1KDM4E | |
| SCHEMBL21186172 | 0.81 | NPC1 (0.55) | NPC1RAB9ARORCRIPK1MAPT | |
| SCHEMBL23657486 | 0.77 | ALDH1A1 (0.69) | NPC1RAB9ARORCRIPK1MAPT | |
| SCHEMBL23607120 | 0.76 | TOP1 (0.61) | NPC1RAB9AALDH1A1KDM4EKMT2A | |
| SCHEMBL21186171 | 0.76 | NPC1 (0.62) | NPC1RAB9AMAPTALDH1A1KMT2A | |
| SCHEMBL19627233 | 0.75 | MAPT (0.58) | NPC1RAB9ARORCRIPK1MAPT | |
| SCHEMBL21186162 | 0.75 | MAPT (0.48) | NPC1RAB9AMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |