Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 4/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186001 | 0.84 | MAPT (0.67) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186198 | 0.80 | NPC1 (0.49) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186008 | 0.78 | MAPT (0.57) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186274 | 0.77 | MAPT (0.51) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186013 | 0.76 | RIPK1 (0.44) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186121 | 0.76 | NPC1 (0.43) | KDM4EHPGDNPC1RAB9AKMT2A | |
| SCHEMBL21186273 | 0.76 | MAPT (0.57) | MAPTHTTLMNAKDM4EPOLB | |
| SCHEMBL21186171 | 0.75 | NPC1 (0.62) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL21186199 | 0.75 | NPC1 (0.59) | MAPTHTTLMNAKDM4EHPGD | |
| SCHEMBL23607120 | 0.73 | TOP1 (0.61) | HTTLMNAKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |