Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186220 | 0.88 | MAPT (0.52) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186273 | 0.76 | MAPT (0.57) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186221 | 0.74 | HCK (0.46) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186281 | 0.73 | MAPT (0.55) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186008 | 0.72 | MAPT (0.57) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186117 | 0.72 | MAPT (0.53) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186205 | 0.72 | SCD (0.64) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186178 | 0.71 | RAB9A (0.72) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186001 | 0.71 | MAPT (0.67) | MAPTNPC1RAB9APKMOPRK1 | |
| SCHEMBL21186280 | 0.70 | NPC1 (0.54) | MAPTNPC1RAB9APKMOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |