Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | RAB9A | P51151 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | PNLIP | P16233 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186001 | 0.84 | MAPT (0.67) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186117 | 0.84 | MAPT (0.53) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186108 | 0.83 | MAPT (0.45) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186008 | 0.80 | MAPT (0.57) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186278 | 0.79 | MAPT (0.55) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186280 | 0.78 | NPC1 (0.54) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186275 | 0.77 | PIK3CG (0.62) | MAPTHTTPOLBNPC1RAB9A | |
| SCHEMBL23607120 | 0.77 | TOP1 (0.61) | HTTKDM4ELMNAHPGDNPC1 | |
| SCHEMBL21186273 | 0.77 | MAPT (0.57) | MAPTHTTPOLBKDM4ELMNA | |
| SCHEMBL21186162 | 0.77 | MAPT (0.48) | MAPTHTTPOLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141980-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |