Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SCD | O00767 | 2/20 | 0.32 |
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30790682 | 0.79 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1SCDTSHRKMT2A | |
| SCHEMBL16039398 | 0.79 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1SCDTSHRKMT2A | |
| SCHEMBL30790686 | 0.79 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1SCDTSHRKMT2A | |
| SCHEMBL16040372 | 0.79 | ALDH1A1 (0.37) | L3MBTL1ALDH1A1SCDTSHRKMT2A | |
| SCHEMBL12548425 | 0.77 | QPCT (0.45) | QPCTLMNAIP6K1 | |
| SCHEMBL12548746 | 0.77 | QPCT (0.45) | QPCTLMNAIP6K1 | |
| SCHEMBL21177939 | 0.75 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SCDADRA1DADRA1A | |
| SCHEMBL30823280 | 0.75 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SCDADRA1DADRA1A | |
| SCHEMBL21187335 | 0.75 | L3MBTL1 (0.38) | L3MBTL1ALDH1A1SCDADRA1DADRA1A | |
| SCHEMBL21178677 | 0.73 | L3MBTL1 (0.38) | L3MBTL1LMNAALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019143678-A1 | DNA-PK INHIBITORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2019-07-25 | — | — | WO | disclosed |