Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.39 |
| ▸ | PLK1 | P53350 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187448 | 0.91 | FGFR1 (0.44) | FGFR1HSD11B1MEN1KMT2AKDM4E | |
| SCHEMBL21187500 | 0.89 | HSD11B1 (0.43) | FGFR1HSD11B1KMT2A | |
| SCHEMBL21187455 | 0.80 | HSD11B1 (0.42) | HSD11B1BTK | |
| SCHEMBL11528755 | 0.77 | FGFR1 (0.63) | FGFR1PLK1MEN1KMT2AKDM4E | |
| SCHEMBL21187491 | 0.76 | FFAR1 (0.34) | HSD11B1KDM4EMAPTHPGDBTK | |
| SCHEMBL21187508 | 0.73 | HSD11B1 (0.37) | FGFR1HSD11B1TP53 | |
| SCHEMBL20697928 | 0.71 | HSD11B1 (0.41) | FGFR1HSD11B1PDE2APDE10A | |
| SCHEMBL21187471 | 0.70 | HSD11B1 (0.39) | HSD11B1CYP1A2PDE2APDE10AHCAR1 | |
| SCHEMBL20697989 | 0.69 | FGFR1 (0.39) | FGFR1HSD11B1MAPTPDE2APDE10A | |
| SCHEMBL24158431 | 0.69 | FGFR1 (0.39) | FGFR1HSD11B1POLBCYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740474-B1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2022-01-05 | — | — | EP | disclosed |
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2020-10-29 | — | — | US | disclosed |
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | ABAT, BRDT, GABBR1 | FGFR1 2730/4885HSD11B1 930/4885PLK1 3241/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.