Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187447 | 0.73 | FGFR1 (0.44) | HSD11B1FGFR1TP53 | |
| SCHEMBL21187448 | 0.73 | FGFR1 (0.44) | HSD11B1FGFR1TP53ALDH1A1KCNH2 | |
| SCHEMBL20697928 | 0.72 | HSD11B1 (0.41) | HSD11B1FGFR1KCNH2DPP4 | |
| SCHEMBL21187472 | 0.72 | FGFR1 (0.33) | HSD11B1FGFR1TP53 | |
| SCHEMBL21187507 | 0.71 | HSD11B1 (0.39) | HSD11B1GRM2TP53ALDH1A1DPP4 | |
| SCHEMBL21187456 | 0.70 | MAPK14 (0.36) | HSD11B1DPP4GABRG2GABRB3GABRA5 | |
| SCHEMBL21187500 | 0.70 | HSD11B1 (0.43) | HSD11B1FGFR1GRM2 | |
| SCHEMBL20698122 | 0.68 | FGFR1 (0.41) | HSD11B1FGFR1TP53KCNH2DPP4 | |
| SCHEMBL21187475 | 0.68 | HSD11B1 (0.36) | HSD11B1GRM2DPP4GABRG2GABRB3 | |
| SCHEMBL20698308 | 0.66 | HSD11B1 (0.36) | HSD11B1FGFR1TP53KCNH2DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3740474-B1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2022-01-05 | — | — | EP | disclosed |
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2020-10-29 | — | — | US | disclosed |
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200339543-A1 | AGRICULTURAL CHEMICALS | ABAT, BRDT, GABBR1 | HSD11B1 930/4885FGFR1 2730/4885GRM2 2297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.