Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.43 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ROS1 | P08922 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21187438 | 0.86 | HSD11B1 (0.42) | HSD11B1NISCHCYP17A1CYP1A2PTPN11 | |
| SCHEMBL21179333 | 0.78 | CLK1 (0.46) | HSD11B1NISCHCYP17A1PTPN11ABL1 | |
| SCHEMBL21187570 | 0.74 | NISCH (0.42) | HSD11B1NISCHCYP17A1MAPK14ROS1 | |
| SCHEMBL21187487 | 0.73 | TDO2 (0.35) | HSD11B1NISCHCYP17A1CYP1A2MAPK14 | |
| SCHEMBL21187496 | 0.73 | NISCH (0.34) | HSD11B1NISCHCYP17A1CYP1A2MAPK14 | |
| SCHEMBL24391199 | 0.72 | KIT (0.42) | MAPK14DRD1 | |
| SCHEMBL21187571 | 0.72 | HSD11B1 (0.48) | HSD11B1NISCHPTPN11 | |
| SCHEMBL6049437 | 0.72 | PTPN11 (0.47) | HSD11B1NISCHPTPN11PDE2APDE10A | |
| SCHEMBL30941565 | 0.71 | HSD11B1 (0.43) | HSD11B1NISCHPTPN11ROS1NPC1 | |
| SCHEMBL30941648 | 0.71 | HSD11B1 (0.47) | HSD11B1NISCHPTPN11ROS1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |