Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23850215 | 0.82 | PRSS1 (0.50) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL29858720 | 0.75 | ALDH1A1 (0.66) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL29966096 | 0.75 | KDM4E (0.54) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL2468448 | 0.75 | KDM4E (0.54) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL473972 | 0.73 | ALDH1A1 (0.65) | JAK2TYK2ALDH1A1HPGDMAPT | |
| SCHEMBL23268318 | 0.73 | JAK2 (0.48) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL3340475 | 0.72 | GAA (0.68) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL3340478 | 0.72 | TYK2 (0.51) | JAK2TYK2ALDH1A1HPGDMAPT | |
| SCHEMBL3340477 | 0.72 | GAA (0.68) | JAK2TYK2ALDH1A1HPGDRAD52 | |
| SCHEMBL23849918 | 0.71 | PRSS1 (0.50) | TYK2ALDH1A1HPGDRAD52GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019141972-A1 | AGRICULTURAL CHEMICALS | GLOBACHEM NV (BE) | 2019-07-25 | — | — | WO | disclosed |