SCHEMBL3340478

SCHEMBL3340478

COc1ccc(C(=N)NO)c(Cl)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 2/20 0.51
JAK2 O60674 1/20 0.51
FLT1 P17948 2/20 0.46
FLT4 P35916 2/20 0.46
KDR P35968 2/20 0.46
RAB9A P51151 2/20 0.43
MAPT P10636 2/20 0.43
KCNH2 Q12809 1/20 0.41
AVPR2 P30518 1/20 0.40
GPR27 Q9NS67 1/20 0.40
NPC1 O15118 1/20 0.40
AKR1C3 P42330 1/20 0.39
AKR1C2 P52895 1/20 0.39
POLB P06746 1/20 0.39
GAA P10253 1/20 0.39
APEX1 P27695 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3275362 0.81 MAPT (0.54) RAB9AMAPTNPC1GAAALDH1A1
SCHEMBL16935787 0.79 CPS1 (0.50) RAB9ANPC1GAAALDH1A1HPGD
SCHEMBL23850215 0.79 PRSS1 (0.50) TYK2JAK2FLT1FLT4KDR
SCHEMBL29042305 0.78 KMT2A (0.43) TYK2JAK2FLT1FLT4KDR
SCHEMBL6448395 0.77 PLAU (0.49) RAB9AMAPTNPC1GAATDP1
SCHEMBL6326108 0.77 MAPT (0.53) RAB9AMAPTPOLBALDH1A1HPGD
SCHEMBL29616566 0.76 SMN1; SMN2 (0.50) TYK2JAK2FLT1FLT4KDR
SCHEMBL4145427 0.76 SMN1; SMN2 (0.50) TYK2JAK2FLT1FLT4KDR
SCHEMBL20608788 0.76 ALDH1A1 (0.49) FLT1FLT4KDRRAB9AMAPT
SCHEMBL3340573 0.75 MEN1 (0.41) RAB9AMAPTNPC1GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4463452-B1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC (US) 2025-07-30 EP disclosed
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 US disclosed
EP-4463452-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER Anima Biotech Inc. (US) 2024-11-20 EP disclosed
WO-2023177700-A2 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2023-09-21 WO disclosed
US-20100160369-A1 S1P1 Agonists and Methods of Making And Using EXELIXIS, INC. (US) 2010-06-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 TYK2 3467/4885JAK2 1781/4885FLT1 4659/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 TYK2 3467/4885JAK2 1781/4885FLT1 4659/4885
US-20100160369-A1 S1P1 Agonists and Methods of Making And Using S1PR1, S1PR5, S1PR3 TYK2 2602/4885JAK2 1649/4885FLT1 162/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.