Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.45 |
| ▸ | TLR2 | O60603 | 1/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13281125 | 0.79 | FGFR1 (0.40) | ERN1TLR2TLR1TLR6FGFR1 | |
| SCHEMBL23092877 | 0.78 | CA1 (0.45) | ERN1TLR2TLR1TLR6FGFR1 | |
| SCHEMBL30203585 | 0.77 | ERN1 (0.66) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL20102297 | 0.73 | CYP2E1 (0.45) | CYP2C9CYP2C19CYP2E1CYP2A6CYP2B6 | |
| SCHEMBL23093177 | 0.71 | ERN1 (0.42) | ERN1TLR2TLR1TLR6CYP2C9 | |
| SCHEMBL19608992 | 0.69 | ERN1 (0.56) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL30203863 | 0.69 | ERN1 (0.56) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL8846481 | 0.69 | ERN1 (0.56) | ERN1TLR2TLR1TLR6SRC | |
| SCHEMBL18529833 | 0.68 | ERN1 (0.50) | ERN1TLR2TLR1TLR6SRC | |
| 2-Methoxybenzaldehyde SCHEMBL27337621 | 0.68 | ALDH1A1 (0.63) | ERN1TLR2TLR1TLR6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225618-A1 | IDO Inhibitors | MAUTINO MARIO (US) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225618-A1 | IDO Inhibitors | IDO1, IDO2, INMT | ERN1 3698/4885TLR2 1606/4885TLR1 1759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.