Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043618 | 0.96 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2118670 | 0.96 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL283704 | 0.89 | THRB (0.66) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8850412 | 0.87 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8850574 | 0.87 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL12332609 | 0.87 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL8851557 | 0.87 | TSHR (0.61) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9066855 | 0.86 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9067681 | 0.86 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL9066211 | 0.86 | TSHR (0.70) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555677-B1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RES AND DEVELOPMENT CORPORATION (US) | 2022-04-20 | — | — | EP | disclosed |
| EP-3458118-B1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RES AND DEVELOPMENT CORPORATION (US) | 2021-10-27 | — | — | EP | disclosed |
| US-10899862-B2 | Hydrophobic intraocular lens | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2021-01-26 | — | — | US | disclosed |
| US-10894111-B2 | High refractive index hydrophilic materials | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2021-01-19 | — | — | US | disclosed |
| EP-3555677-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | Benz Research And Development Corporation (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-3458118-A1 | HYDROPHOBIC INTRAOCULAR LENS | Benz Research And Development Corporation (US) | 2019-03-27 | — | — | EP | disclosed |
| US-10196470-B2 | Hydrophobic intraocular lens | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2019-02-05 | — | — | US | disclosed |
| US-20180334520-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-11-22 | — | — | US | disclosed |
| US-20180169296-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-06-21 | — | — | US | disclosed |
| WO-2018112180-A1 | HIGH REFRACTIVE INDEX HYDROPHILIC MATERIALS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2018-06-21 | — | — | WO | disclosed |
| WO-2017200934-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2017-11-23 | — | — | WO | disclosed |
| US-20170327615-A1 | HYDROPHOBIC INTRAOCULAR LENS | BENZ RESEARCH AND DEVELOPMENT CORP. (US) | 2017-11-16 | — | — | US | disclosed |
| US-8318824-B2 | Hydrophilic polyolefin sintered body | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-11-27 | — | — | US | disclosed |
| US-20120095121-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2012-04-19 | — | — | US | disclosed |
| EP-2174975-A1 | HYDROPHILIC POLYOLEFIN SINTERED BODY | Asahi Kasei Chemicals Corporation (JP) | 2010-04-14 | — | — | EP | disclosed |