Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.66 |
| ▸ | PAM | P19021 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19604562 | 1.00 | HTR2A (0.66) | HTR2APAMGRIK1GRIK2TSHR | |
| SCHEMBL5475692 | 1.00 | HTR2A (0.66) | HTR2APAMGRIK1GRIK2TSHR | |
| SCHEMBL5475689 | 1.00 | HTR2A (0.66) | HTR2APAMGRIK1GRIK2TSHR | |
| SCHEMBL2170349 | 0.83 | HTR2A (0.70) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL4029905 | 0.83 | HTR2A (0.59) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL107851 | 0.83 | HTR2A (0.70) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL14037582 | 0.83 | HTR2A (0.70) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL107852 | 0.83 | HTR2A (0.70) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL7903419 | 0.83 | HTR2A (0.59) | HTR2APAMGRIK1GRIK2IDO1 | |
| SCHEMBL25189137 | 0.80 | HTR2A (0.61) | HTR2APAMGRIK1GRIK2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190225573-A1 | VINYLOGOUS PHENETHYLAMINES AS NEUROTRANSMITTER RELEASERS | RES TRIANGLE INST (US) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190225573-A1 | VINYLOGOUS PHENETHYLAMINES AS NEUROTRANSMITTER RELEASERS | SLC18A2, SLC6A2, SLC18A3 | HTR2A 10/4885PAM 1537/4885GRIK1 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.